Acetyl Tetrapeptide-5 Cosmetic Peptide anti wrinkle cream CAS NO.820959-17-9

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INCI name: Acetyl Tetrapeptide-5

Reference:Eyeseryl

Cas No: 820959-17-9

Formula: C20H28N8O7

Molecular:492

Sequence:Ac-Beta-Ala-His-Ser-His-OH

Purity:>98%

Odor: no

Grade: cosmetic

Source: synthetic

Stability: stable

Solubility: soluble in water

Peptide Solution: 0.1%

Capacity: 5000g per month

Appearance: white powder

Function

While this ingredient is most often found in eye creams it is also found in shampoo, conditioner, frizz serums, lotions, creams, lip treatments, cleansers, after-sun lotion, soap and body lotions.

Acetyl tetrapeptisde-5 is a known humectant or hydroscopic moisturizer which helps reduce eye puffiness, improve skin elasticity as well as overall smoothness. This is done by attracting water from deep within in the skin to the outer-most layer of the skin (stratum corneum), taking advantage of this compounds hydroscopic properties (Making Cosmetics). Humectant rich formulas have also been used to treat xerosis (abnormally dry skin) successfully (PubMed). Humectants can also play an important role as emulsifiers within an overall formulation according to the Cosmetics Database.

Description

Acetyl tetrapeptide-5 is a part of this controversy. Found primarily in eye creams, acetyl tetrapeptide-5 has been shown to reduce puffiness and swelling by changing the micro-circulation in the skin in this area, making it less permeable to fluid,regular use of 0.001% Eyeseryl can reduce the leaking of interstitial fluid into the eye by up to 50% — meaning your eyes have far less swelling and puffing.

How Acetyl tetrapeptide-5 Works

How this works is a bit complex.Eyeseryl works in two ways. First, it inhibits glycation in the skin around the eyes. Glycation normally causes abnormal, disorganized cross-linking in collagen fibers. Rather than having all of your collagen fibers working together in a unified, organized fashion, glycation causes skin to be less elastic. 

The second way Eyeseryl works is by changing the permeability of your blood vessels in the region. (Yes, this sounds scary, but it actually is no scarier than putting pressure on a wound — you are simply changing the circulation).

Applications

While this ingredient is most often found in eye creams it is also found in shampoo, conditioner, frizz serums, lotions, creams, lip treatments, cleansers, after-sun lotion, soap and body lotions.