PRL-8-53 CAS NO.51352-87-5

Introduction

 prl-8-53 (chemical name methyl 3-(2-(benzyl(methyl)amino)ethyl)benzoate) is a synthetic nootropic compound discovered in 1972 and patented in 1975 by the late dr. nikolaus hansl, a neuropharmacologist at creighton university in omaha, nebraska. preliminary animal tests indicated that the compound was both safe and significantly nootropic, boosting avoidance learning in rodents with no adverse effects. but the real interest in prl-8-53 was sparked by a 1978 study on human volunteers, which showed that a single dose of the compound could improve word retention scores by more than 200%.

Function

 ·Improved Memory
· Increased Learning Ability
· Improved Cognitive Processing 
· Heightened Reflexes
· Heightened Perception
· Reduced Anxiety
· Reduced Depression

Application

The exact mechanism of action of PRL-8-53 remains unknown. Doses up to 200 mg/kg are not observed to have stimulant properties, and a dosage of 20 mg/kg does not potentiate the effects of dextroamphe tamine in rats. It displays cholinergic properties, and potentiates dopamine while partially inhibiting serotonin.
PRL-8-53 is relatively non-toxic, with an oral LD50 in mice of 860 mg/kg, giving the drug a high therapeutic index. Doses above 8 mg/kg have brief hypotensiveeffects in the canine.High doses depress motor activity in the rat and mouse, with the ED50 for a 50% reduction in motor activity of mice at 160 mg/kg. PRL-8-53 displays spasmolytic effects

Specification

Packaging Details:
25kgs packaging Fiber drum outside and plastic bag inside 1-25kgs packaging aluminium bag
outside and double plastic bag inside.