China (Mainland)
Anti tumor drug 99% Exemestane/Aromasin powder BP/USP Standard CAS NO.107868-30-4
- Min.Order: 100 Gram
- Payment Terms: T/T,
- Product Details
Keywords
- Exemestane
- Aromasin Powder
- Exemestane powder
Quick Details
- ProName: Anti tumor drug 99% Exemestane/Aromasi...
- CasNo: 107868-30-4
- Appearance: white powder
- Application: pharmaceuticals
- DeliveryTime: Within 3-5 days
- PackAge: 1Kgs/Tin,25Kgs/Carton
- Port: shanghai
- ProductionCapacity: 500 Metric Ton/Day
- Purity: 99%
- LimitNum: 100 Gram
Superiority
GMP Factory, cheap Price
Details
Product Description of Anti tumor drug 99% Exemestane/Aromasin powder CAS 107868-30-4
Name: exemestane
CAS Number: 107868-30-4
Molecular formula: C20H24O2
Molecular weight: 296.40300
Exact Mass: 296.17800
PSA: 34.14000
LogP: 4.02950
Physicochemical properties
Appearance and traits: white to pale yellow crystalline powder
Density: 1.13 g/cm3
Melting point: 155.13°C
Boiling point: 453.7oC at 760 mmHg
Flash point: 169oC
Refractive index: 1.572
Storage conditions: Store in original container in a cool dark place.
Steam pressure: 2.02E-08mmHg at 25°C
Specification:
|
TEST ITEMS |
SPECIFICATION |
RESULTS |
|
Description |
: White Crystalline Powder |
White Powder |
|
Identification |
: Positive |
Positive |
|
Assay(by HPLC) |
: 98.0~102.0% |
98.64% |
|
Absorbance(E1cm) |
: 465~495 |
482.5 |
|
Melting Point |
: 191~195°C |
193.5~195.0°C |
|
Loss On Drying |
: 0.5%max |
0.19% |
|
Specific Rotation |
: +288°~ +298° |
+290.2° |
|
Residue On Ignition |
: 0.1%max |
0.03% |
|
Related Substances |
: Total:1.5%max |
<1.3% |
|
|
Single:0.5%max |
<0.4% |
|
Residue Solvents |
: 0.2%max |
0.10% |
|
Heavy Metals |
: 20PPm max |
<10PPm |
|
|
|
|
|
Conclusion |
The specification conform with enterprise standard. |
|
Use
1. Second-generation aromatase inhibitors for the treatment of metastatic breast cancer and as an adjunct to early breast cancer.
2. Developed by Pharmacia & Upjohn Company. Approved by the U.S. FDA in October 1997. Antineoplastic Agent, Second Generation Aromatase Inhibitor. Exemestane is the first oral hormonal agent that can be selectively targeted and permanently In combination with aromatase, once exemestane binds to the enzyme, the enzyme can never be remade estrogen. It can inhibit the supply of estrogen to cancer cells and help prevent cells from continuing to grow. It is used to treat metastatic disease. Breast cancer and its use as an adjunct to early breast cancer.
3. This product is a second-generation aromatase inhibitor. It can be irreversibly combined with aromatase to inactivate it, thus preventing the biosynthesis of estrogen. Clinically for the treatment of metastatic breast cancer and early breast cancer Adjuvant therapy with exact curative effect, good tolerability and relatively few side effects