99% Purity Bodybuilding Peptide Ace 031 Powder Hormone Peptide Ace-031

High-Purity 99% ACE 031 ACE031 ACE-031 ACVR2B myostatin inhibitor CAS 1356922-05-8

Description
ACE-031, also referred to as ACVR2B or ActRIIB-IgG1, is a synthetically produced protein that was originally developed by two bio-pharmaceutical companies, namely Acceleron and Shire, for its potential ability to inhibit myostatin and other naturally occurring proteins that limit muscle growth. It was hypothesized that ACE-031 would act as a decoy receptor for the catabolic proteins, specifically myostatin, and bind to them in an effort to keep them away from muscle fibers. Numerous studies have been conducted to determine if ACE-031 is an effective treatment for children who have Duchenne Muscular Dystrophy (DMD).

Specification
Name: ACE-031
Synonyms: actr2b, ACTRIIB, ACVR2B, HTX4,
Appearance: White powder

Usage
ACE-031 acts by binding to proteins that normally signal through a particular activin receptor called ActRIIB. Myostatin and other related proteins signal through this receptor to limit muscle growth. When ACE-031 binds to these proteins, it prevents them from interacting with the ActRIIB receptor, thus allowing muscle to grow. The critical difference between ACE-031 and antibodies to myostatin is that ACE-031 inhibits multiple regulators of muscle mass in addition to myostatin. In preclinical studies, the end result is a greater increase in muscle mass than can be achieved by blocking myostatin alone. In Duchenne, the goal is to offset the loss of muscle due to the lack of dystrophin by increasing the production of new muscle.